International Advisory Board
Prof. Romuald Będziński
Full Member of the Polish Academy of Sciences, Wrocław, Poland
Polish engineer, mechanic, specialist in biomedical engineering, professor of technical sciences, honorary doctor of the Medical University of Wrocław, full member of the Polish Academy of Sciences, long-time academic teacher at the Wrocław University of Science and Technology.
Polish engineer, mechanic, specialist in biomedical engineering, professor of technical sciences, honorary doctor of the Medical University of Wrocław, full member of the Polish Academy of Sciences, long-time academic teacher at the Wrocław University of Science and Technology.
Prof. Marek Czosnyka
Professor Emeritus of Brain Physics, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, UK
Professor Marek Czosnyka, based in Cambridge since 1991, has pioneered studies on cerebral autoregulation and cerebrospinal dynamics, publishing over 800 papers. He developed bedside ICP monitoring, multimodal systems, and diagnostic models for brain disorders. His innovations include methods for assessing cerebral autoregulation, CSF dynamics, and non-invasive cerebral perfusion.
The ability of the brain to perform its analytical, emotional and executive functions depends upon an intact blood supply and competent buoyancy mechanisms. Evidence that majority of brain disorders have meaningful vascular components, being either a reason or a consequence of impending pathology, grows continuously. Therapeutical strategy crucially depends on assessment of cerebrovascular abnormality, including dysautoregulation, abnormal distribution of blood flow, ischaemia and hyperemia.
Over the past 20 years Professor Czosnyka has been conducting studies on methodology, clinical applications and models in clinical and experimental neuroscience aimed on autoregulation of cerebral blood flow and cerebrospinal dynamics (with a special attention to dynamics of Intracranial Pressure (ICP)), publishing over 800 papers in scientific press. He focused on interactions between intracranial pressure, cerebral autoregulation, and cerebral blood flow.
Last 34 years (from 1991) Professor Czosnyka spent in Cambridge, U.K. where he gained experience in setting up and steering large-scale scientific projects. He started with organizing computer-assisted bed-side monitoring of ICP in neurological critical care 4-beds annex and a mobile trolley for computerized infusion test to diagnose patients with hydrocephalus. Gradually he extended the system to multimodal bed-side monitoring (including cerebral blood flow, brain oxygenation, microdialysis). Now these systems are in daily use in 21-beds Neuro-Critical Care Unit controlling modern bed-side monitoring facilities. He supervised and coordinated a variety of scientific projects being conducted there (for PhD students and visiting scholars).
Professor Marek Czosnyka’s three most important scientific achievements may be listed as follows:
- Invention of methods for the continuous assessment of cerebral autoregulation and cerebrovascular reactivity and demonstration that they strongly determine outcome following head injury.
- Building system for diagnosing based on mathematical modelling of CSF dynamics leading to clinical tests able to differentiate brain atrophy (e.g. Alzheimer disease) and remediable hydrocephalus.
Invention of the method for non-invasive assessment of cerebral perfusion pressure.
Prof. Zofia Czosnyka
Senior Research Associate, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, UK
Dr. Zofia Czosnyka has worked in Cambridge since 1992, focusing on hydrocephalus management. She founded the Shunt Evaluation Laboratory in 1994, testing 21 shunt types and producing influential publications. Since 1999, she has led advanced monitoring of intracranial pressure, cerebral autoregulation, and CSF circulation disorders.
Her professional activity in Cambridge (since 1992) has been invariantly linked with the management of hydrocephalus. Growing number of cases of hydrocephalus seen every year, particularly in elderly, new understanding of the role of disturbance in cerebrospinal fluid (CSF) circulation and its biochemical makeup in brain diseases extending beyond traditional boundaries of hydrocephalus made this area of clinical neuroscience both challenging and innovative
In 1994 she set up and run Shunt Evaluation Laboratory- world renowned centre for independent evaluation of hydrodynamic properties of hydrocephalus shunts enabling precise shunt testing and tailoring use of different types of shunts in patients presenting with selective CSF circulatory problems. The Laboratory tested 21 types of valves producing number of publications and well known in the UK ‘blue reports’ containing descriptions, indications, literature review of the most popular and innovative type of shunts
Since 1999 she has run physiological monitoring unit (including computerized infusion tests and overnight monitoring of intracranial pressure) to diagnose hydrocephalic patients. These works have already gained some recognition and recently, she extended their scope to monitoring cerebral autoregulation, pressure-reactivity, analysis of vasogenic waveforms and viscoelastic properties of the brain tissue, as well as on modern brain imaging techniques (in co-operation).
Dr Zofia Czosnyka’s three most important achievements in this field include:
- Set up criteria for in-vivo assessment of hydrocephalus shunt, useful in avoiding unnecessary shunt revisions
- Description of the link between failure of CSF circulation in hydrocephalus and haemodynamic failure, particularly disorder of autoregulation of CBF and cerebral pressure-reactivity
- Popularization of infusion tests and overnight ICP monitoring in diagnosis of diseases linked to disorders of CSF circulation.
Prof. Olga Golubnitschaja, MD
Head of 3P Medicine, University Hospital, Bonn, Germany
Prof. Dr. Olga Golubnitschaja leads the world’s first 3P Medicine Unit at the University Hospital Bonn. With over 400 publications, a Google Scholar h-index of 60, and prestigious awards, she is a global leader in predictive, preventive, and personalized medicine. Since 2021, she has been President of EPMA, representing 50+ countries.
Prof. Dr. Olga Golubnitschaja is the Head of the world’s first Predictive, Preventive, and Personalised (3P) Medicine Unit at the Department of Radiation Oncology, University Hospital Bonn, Rheinische Friedrich-Wilhelms-Universität Bonn, Germany. Her multidisciplinary education spans journalism, biotechnology, and medicine, and she has held prestigious research fellowships in Austria, Russia, the UK, Germany, the Netherlands, and Switzerland. Her research focuses on early and predictive diagnostics in pediatrics, neurosciences, and cancer.
Prof. Dr. Golubnitschaja has authored over 400 international publications, including research and review articles, position papers, books, book chapters, and congress contributions. Her work is at the forefront of predictive, preventive, and personalised medicine (3PM), with primary research interests in sub-optimal health conditions, pre- and perinatal diagnostics, cardiovascular diseases, neurodegenerative pathologies, and predictive diagnostics in cancer and diabetes. Her Google Scholar h-index is an impressive 60, with annual citations exceeding 650 since 2019.
She has received numerous awards, including the National and International Fellowships of the Alexander von Humboldt Foundation, the Eiselsberg Prize and the Highest Prize in Medicine in Austria, the Springer Nature Award, and the EMA Award.
Since September 2021, Prof. Dr. Olga Golubnitschaja has been the President of the European Association for Predictive, Preventive, and Personalised Medicine (EPMA), based in Brussels, leading network spanning over 50 countries. From 2009 to 2021, Dr. Golubnitschaja served as the EPMA Secretary-General. She is also the Editor-in-Chief of the EPMA Journal (Clarivate IF: 8.836, Scopus CiteScore: 11.3) and the Springer Nature book series Advances in Predictive, Preventive, and Personalised Medicine.
Prof. Dr. Golubnitschaja represents Europe in the EDR-Network at the National Institutes of Health (USA) and serves as a reviewer for over 50 clinical and scientific journals, as well as for international funding bodies in Europe and beyond. She is a recognized evaluation expert at the European Commission and contributed to the development of the 3PM-related content in the European “Horizon 2020” program (2010–2013). Currently, Prof. Dr. Golubnitschaja holds leadership roles as Vice-Chair of the Habilitation Committee (responsible for all medical specializations) at the Medical Faculty of the University of Bonn and as Vice-Chair of the Evaluation Panel for Marie Curie Mobility Actions at the European Commission in Brussels.
Prof. Dr. Olga Golubnitschaja will serve as a member of the International Advisory Committee of our Congress.
Prof. Effie Kapsalaki
University of Thessaly, Larissa, Greece
Dr. Kapsalaki, a professor of diagnostic radiology and specialized neuroradiologist, has been a faculty member at the University of Thessaly, Greece, since 2005 and Head of MR Imaging at Euromedica since 2021. With over 100 publications and 200 presentations, her work focuses on brain tumors, epilepsy, PD, and cerebrovascular diseases.
Dr Kapsalaki is a professor of diagnostic radiology and a subspecialized neuroradiologist.
She is a faculty member of the University of Thessaly in Larissa Greece since September 2005. Since October 2021 she is also the head of MR imaging at the Euromedica medical imaging group, a private diagnostic center with state of the art imaging modalities in Greece.
Dr Kapsalaki has graduated from the Medical School of the University of Athens, Greece in 1991 and has done her training in radiology at the Ag Sofia Children’s Hospital in Athens from May 1992 till May 1993 and has completed her training in radiology at Areteion Hospital in Athens in July 1996.
She was a fellow of neuroradiology at the Medical College of Georgia, in Augusta, GA and at Mercer University in Macon GA.
In 2005 she was elected a lecturer at the University of Thessaly.
She has more than 100 publications in peer reviewed journals and over 200 oral and poster presentations at national and international meetings.
Most of her publications and presentations are on neuroradiology and particularly brain tumors, epilepsy, PD, cerebrovascular diseases.
She was an invited speaker in more that 100 national and international meetings.
She is responsible for Radiology I teaching 4th year medical students during the first semester and she is responsible for 2 elective lessons in neuroradiology ( emergency neuroradiology and clinical and functional neuroradiology) during the second semester.
She is responsible for the neuroradiology protocols (clinical and research) at the University Hospital of Larissa and she also performs lectures on neuroradiology for the radiology and other specialty residents.
Dr Kapsalaki was also the elected Greek delegate at the European Society of Neuroradiology 2018-2020.
She has organized several national and international meetings in Greece.
Kurt Krapfenbauer, PhD
Vice President at European Association for Predictive, Preventive and Personalised Medicine (EPMA), Austria
Dr. Kurt Krapfenbauer, a senior scientist specializing in biomarker research, has held leadership roles at Hoffman-La Roche, Novartis, and 3P-Medicon. With over 55 publications, seven patents, and expertise in predictive medicine, he is VP of International Affairs at EPMA. His talk will focus on AI’s role in advancing personalized oncology care.
Dr. Kurt Krapfenbauer began his career in 1995 at the Ludwig Boltzmann Institute for Radiation Chemistry, University of Vienna, and continued in 1996 as a scientist at the Institute for Amino Acid Research at the Medical University of Vienna. Following his studies, he expanded his expertise by moving to Basel, where he contributed to biomarker research at Hoffman-La Roche. He subsequently took on the role of Head of Biomarker Research at the Novartis Institutes for Biomedical Research.
Over his career, Dr. Krapfenbauer has been responsible for various critical functions, including Research & Development, Manufacturing Operations, Technical Operations, and Quality Assurance. His expertise was further broadened through postgraduate studies, earning a qualification as a Qualified Person. In this capacity, he actively works as a freelance consultant.
Dr. Krapfenbauer is an accomplished senior scientist with extensive experience in biomarker research, particularly in the development and validation of biomarker assays. He is a founding member of the European Predictive, Preventive, and Personalized Medicine Association (EPMA), established in 2008 in Brussels, and co-founder of the 3P-Medicon startup company in 2020.
He served as Vice President for European Affairs at EPMA from 2008 to 2020 and has held the role of Vice President for International Affairs since 2021.
He holds a Ph.D. and a master’s degree in chemistry and bioanalytical chemistry from the University of Vienna. Dr. Krapfenbauer is the inventor of more than seven international patents, which earned him the Roche Inventory Award in 2005. Additionally, he has authored over 55 scientific publications in the field of biochemical research.
Dr. Krapfenbauer will talk about: The integration of AI in the pharmaceutical industry and biomarker research to advance predictive, preventive, and personalized approaches to oncological patient care.
Prof. Jerzy W. Rozenblit
University Distinguished Professor and Raymond J. Oglethorpe Endowed Chair in the Department of Electrical and Computer Engineering (ECE) at the University of Arizona, in Tucson, Arizona, USA
Jerzy W. Rozenblit, University Distinguished Professor and Raymond J. Oglethorpe Endowed Chair at the University of Arizona, is a pioneer in engineering computer-based systems (ECBS). He founded the Model-Based Design Lab and developed innovative systems for minimally invasive surgical training, improving patient safety. His work spans VLSI design, embedded systems, and national security.
Jerzy W. Rozenblit is a University Distinguished Professor and Raymond J. Oglethorpe Endowed Chair in the Department of Electrical and Computer Engineering (ECE) at the University of Arizona, in Tucson, Arizona. He also holds a joint appointment as Professor of Surgery at the University of Arizona College of Medicine. From 2003 to 2011 he served as the ECE Department Head. During his tenure at the University of Arizona, he established the Model-Based Design Laboratory with major projects in complex systems design hardware software codesign, modeling, and computer-aided minimally-invasive surgical training. He presently serves as Director of the Life-Critical Computing Systems Initiative, a research enterprise intended to improve the reliability and safety of technology in life-critical applications.
Rozenblit is one of the founders of the area known as the engineering of computer-based systems (ECBS). His key contributions are seminal works in model-based design that established the theoretical basis of ECBS and bringing ECBS principles to practice in a number of significant engineering applications, namely VLSI design and manufacturing embedded systems design and testing, computer-assisted surgery (clinical medicine), and national security.
Specific technical innovations of his approach include the development of heuristics for design space search (a problem well known and proven to be NP-complete). The developed heuristics that use a rule-based approach to reduce the search complexity from exponential to polynomial and allow for rapid construction of simulatable design models.
Leveraging from his work in design and modeling. Rozenblit developed the model-based codesign approach that integrated hardware and software development paths, solving the “model continuity” problem by providing techniques to map formal specification onto executable design models. Rozenblit’s recent work in design and engineering of systems for minimally invasive surgical training and computer-assisted surgery has strong societal implications, namely the improvement of patients’ safety. He has developed the first ever system that improves the situational awareness in laparoscopic surgery using vision, sensor, and haptic-based guidance.
In 2009, he was named University Distinguished Professor by the University of Arizona and its Arizona Board of Regents for exceptional contributions to research and undergraduate education.
Prof. Thomas A. Zelniker, MD
Senior Physician, Director of the Cardiometabolic Clinic, Director of the Intermediate Care Unit, and Inpatient Service, Vienna General Hospital, Medical University of Vienna, Austria
Senior Physician, Director of the Cardiometabolic Clinic, Director of the Intermediate Care Unit, and Inpatient Service, Vienna General Hospital, Medical University of Vienna, Austria
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